We are Integrated Biosciences.

Cellular rejuvenation with optogenetics and small molecules

We combine synthetic biology and machine learning to control cellular stress responses for next-generation therapeutics.

The Targets

The integrated stress response (ISR) is a cellular stress response that contributes to diseases including neurodegeneration, cancer, diabetes, osteoarthritis, and other age-associated diseases. Targeting the ISR with small molecule therapeutics would be disease-modifying and help to mediate healthy aging.

The Technology

We have developed proprietary synthetic biology technology that allows us to virtually subject cells to stress, discover drugs targeting the ISR, and rapidly identify targets using light. We have also developed next-generation deep learning approaches to identifying novel small molecules that will accelerate our discovery efforts.

Advances in synthetic biology, machine learning, and drug discovery now enable us to fundamentally target cellular stress responses common to multiple diseases.

Led by Felix Wong and Max Wilson and advised by James J. Collins and Timothy K. Lu, as bioengineers from Harvard, MIT, and UC Santa Barbara, we have assembled an all-star team of PhD-trained scientists with expertise in synbio, microbiology, computational biology, and drug discovery. We're looking for scientists that believe, and are willing to bet, that the future lies at the intersection of synbio and machine learning for healthy aging. Our team has over 50 combined years of academic expertise, published in the top scientific journals, and founded several biotechnology companies.

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Our Team

Felix Wong, Ph.D.
Co-founder and CEO

Max Wilson, Ph.D.
Co-founder and Scientific Advisory Board

Ryan Lach

Satotaka Omori

Taivan Batjargal
Advisory Board

Max Wilson, Ph.D.
Co-founder and Scientific Advisory Board

James J. Collins, Ph.D.
Chair of the Scientific Advisory Board

Timothy K. Lu, Ph.D.
Scientific Advisory Board